http://comic-con.gamespot.com/story/6324713/at-the-crossroads-of-steroids-baseball-and-deus-ex
The takeaway: Sometimes, people take sci-fi for granted. Audiences may not really appreciate the amount of work and research that goes into creating a world that is not only fantastic, but also realistic and relatable. By incorporating real science and sociology into its universe, the development team of Deus Ex: Human Revolution hopes that people will be able to instantly understand its message and what the implications are of Adam Jensen's actions in the game.
Did not read the article (Ha-hah!... Slashdot) but the quote there seems fairly defensive, almost apologetic "You won't 'appreciate' this game because it's too sci-fi for you".
Sci-Fi isn't about believable science or realistic sociology it's all about exploring new ideas within a framework. From what I've seen (which is limited to a few gameplay videos / teaser trailers) the world setting is based on the typical 80s/90s dystopian future (nothing wrong with that) populated with characters who can increase various attributes and a world designed around this mechanic in mind so that subtlety can be introduced to the player (i.e. if you had a psychic bartender he could just give you what you wanted before you asked for it). Seemingly small things like that help build the world.
The part that I think this game will suffer from most is overuse of genre clichés and maybe game engine (it better be damn obvious and fun to attempt different resolutions otherwise most people will go the "shoot stuff" route, bypassing any and all subtlety). These two keys are extremely important and really either one done well can make or break a game; I mean, I can forgive
Street Fighter for its lack of depth due to its natural gameplay just as I can forgive
Fallout its tedious gameplay for its stunning depth.